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BDNF Activates mTOR to Regulate GluR1 Expression Required for Memory Formation

BACKGROUND: The mammalian target of Rapamycin (mTOR) kinase plays a key role in translational control of a subset of mRNAs through regulation of its initiation step. In neurons, mTOR is present at the synaptic region, where it modulates the activity-dependent expression of locally-translated protein...

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Detalles Bibliográficos
Autores principales: Slipczuk, Leandro, Bekinschtein, Pedro, Katche, Cynthia, Cammarota, Martín, Izquierdo, Iván, Medina, Jorge H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695538/
https://www.ncbi.nlm.nih.gov/pubmed/19547753
http://dx.doi.org/10.1371/journal.pone.0006007