Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors

RATIONALE: We evaluated the effects of haloperidol and its metabolites on capsaicin-induced mechanical hypersensitivity (allodynia) and on nociceptive pain induced by punctate mechanical stimuli in mice. RESULTS: Subcutaneous administration of haloperidol or its metabolites I or II (reduced haloperi...

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Detalles Bibliográficos
Autores principales: Entrena, José M., Cobos, Enrique J., Nieto, Francisco R., Cendán, Cruz M., Baeyens, José M., Del Pozo, Esperanza
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695546/
https://www.ncbi.nlm.nih.gov/pubmed/19326101
http://dx.doi.org/10.1007/s00213-009-1513-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695546/
https://www.ncbi.nlm.nih.gov/pubmed/19326101
http://dx.doi.org/10.1007/s00213-009-1513-8

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