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Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors
RATIONALE: We evaluated the effects of haloperidol and its metabolites on capsaicin-induced mechanical hypersensitivity (allodynia) and on nociceptive pain induced by punctate mechanical stimuli in mice. RESULTS: Subcutaneous administration of haloperidol or its metabolites I or II (reduced haloperi...
Autores principales: | Entrena, José M., Cobos, Enrique J., Nieto, Francisco R., Cendán, Cruz M., Baeyens, José M., Del Pozo, Esperanza |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695546/ https://www.ncbi.nlm.nih.gov/pubmed/19326101 http://dx.doi.org/10.1007/s00213-009-1513-8 |
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