PDE4 inhibitors as potential therapeutic agents in the treatment of COPD-focus on roflumilast

Chronic obstructive pulmonary disease is characterized by a rapid decline in lung function due to small airway fibrosis, mucus hypersecretion and emphysema. The major causative factor for COPD is cigarette smoking that drives an inflammatory process that gives rise to leukocyte recruitment, imbalanc...

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Detalles Bibliográficos
Autores principales: Boswell-Smith, Victoria, Spina, Domenico
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695611/
https://www.ncbi.nlm.nih.gov/pubmed/18044684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695611/
https://www.ncbi.nlm.nih.gov/pubmed/18044684

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