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Acute or chronic stress induce cell compartment-specific phosphorylation of glucocorticoid receptor and alter its transcriptional activity in Wistar rat brain

Chronic stress and impaired glucocorticoid receptor (GR) feedback are important factors for the compromised hypothalamic–pituitary–adrenal (HPA) axis activity. We investigated the effects of chronic 21 day isolation of Wistar rats on the extrinsic negative feedback part of HPA axis: hippocampus (HIP...

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Detalles Bibliográficos
Autores principales: Adzic, Miroslav, Djordjevic, Jelena, Djordjevic, Ana, Niciforovic, Ana, Demonacos, Constantinos, Radojcic, Marija, Krstic-Demonacos, Marija
Formato: Texto
Lenguaje:English
Publicado: BioScientifica 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695659/
https://www.ncbi.nlm.nih.gov/pubmed/19406955
http://dx.doi.org/10.1677/JOE-08-0509