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The Glyceraldehyde-3-Phosphate Dehydrogenase and the Small GTPase Rab 2 Are Crucial for Brucella Replication

The intracellular pathogen Brucella abortus survives and replicates inside host cells within an endoplasmic reticulum (ER)-derived replicative organelle named the “Brucella-containing vacuole” (BCV). Here, we developed a subcellular fractionation method to isolate BCVs and characterize for the first...

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Detalles Bibliográficos
Autores principales: Fugier, Emilie, Salcedo, Suzana P., de Chastellier, Chantal, Pophillat, Matthieu, Muller, Alexandre, Arce-Gorvel, Vilma, Fourquet, Patrick, Gorvel, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695806/
https://www.ncbi.nlm.nih.gov/pubmed/19557163
http://dx.doi.org/10.1371/journal.ppat.1000487