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Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA
RNA enzymes have been developed that undergo self-sustained replication at a constant temperature in the absence of proteins1. These RNA molecules amplify exponentially through a cross-replicative process, whereby two enzymes catalyze each other’s synthesis by joining component oligonucleotides. Oth...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695811/ https://www.ncbi.nlm.nih.gov/pubmed/19234448 http://dx.doi.org/10.1038/nbt.1528 |