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The blood–brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain(1)
Drugs to treat African trypanosomiasis are toxic, expensive and subject to parasite resistance. New drugs are urgently being sought. Although the existing drug, eflornithine, is assumed to reach the brain in high concentrations, little is known about how it crosses the healthy and infected blood–bra...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695853/ https://www.ncbi.nlm.nih.gov/pubmed/18823367 http://dx.doi.org/10.1111/j.1471-4159.2008.05706.x |