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CCHCR1 Is Up-Regulated in Skin Cancer and Associated with EGFR Expression

Despite chronic inflammation, psoriatic lesions hardly ever progress to skin cancer. Aberrant function of the CCHCR1 gene (Coiled-Coil α-Helical Rod protein 1, HCR) within the PSORS1 locus may contribute to the onset of psoriasis. As CCHCR1 is expressed in certain cancers and regulates keratinocyte...

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Detalles Bibliográficos
Autores principales: Suomela, Sari, Elomaa, Outi, Skoog, Tiina, Ala-aho, Risto, Jeskanen, Leila, Pärssinen, Jenita, Latonen, Leena, Grénman, Reidar, Kere, Juha, Kähäri, Veli-Matti, Saarialho-Kere, Ulpu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696036/
https://www.ncbi.nlm.nih.gov/pubmed/19551138
http://dx.doi.org/10.1371/journal.pone.0006030