Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

Ebola Zaire virus is highly pathogenic for humans, with case fatality rates approaching 90% in large outbreaks in Africa. The virus replicates in macrophages and dendritic cells (DCs), suppressing production of type I interferons (IFNs) while inducing the release of large quantities of proinflammato...

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Detalles Bibliográficos
Autores principales: Chang, Tsung-Hsien, Kubota, Toru, Matsuoka, Mayumi, Jones, Steven, Bradfute, Steven B., Bray, Mike, Ozato, Keiko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696038/
https://www.ncbi.nlm.nih.gov/pubmed/19557165
http://dx.doi.org/10.1371/journal.ppat.1000493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696038/
https://www.ncbi.nlm.nih.gov/pubmed/19557165
http://dx.doi.org/10.1371/journal.ppat.1000493

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