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Cardiomyocyte Contractile Dysfunction in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease

OBJECTIVES: Ample clinical and experimental evidence indicated that patients with Alzheimer's disease display a high incidence of cardiovascular events. This study was designed to examine myocardial histology, cardiomyocyte shortening, intracellular Ca(2+) homeostasis and regulatory proteins, e...

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Detalles Bibliográficos
Autores principales: Turdi, Subat, Guo, Rui, Huff, Anna F., Wolf, Eliza M., Culver, Bruce, Ren, Jun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696039/
https://www.ncbi.nlm.nih.gov/pubmed/19551139
http://dx.doi.org/10.1371/journal.pone.0006033