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Thermostabilisation of the neurotensin receptor NTS1

Structural studies on G protein-coupled receptors (GPCRs) have been hampered for many years by their instability in detergent solution and by the number of potential conformations that receptors can adopt. Recently, the structures of the β(1) and β(2) adrenergic receptors and the adenosine A(2a) rec...

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Detalles Bibliográficos
Autores principales: Shibata, Yoko, White, Jim F., Serrano-Vega, Maria J., Magnani, Francesca, Aloia, Amanda L., Grisshammer, Reinhard, Tate, Christopher G.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696590/
https://www.ncbi.nlm.nih.gov/pubmed/19422831
http://dx.doi.org/10.1016/j.jmb.2009.04.068