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Synergistic Induction of Apoptosis in Primary B-CLL Cells after Treatment with Recombinant Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand and Histone Deacetylase Inhibitors

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is currently being investigated as a therapeutic agent for a variety of malignancies, as it triggers apoptosis specifically in transformed cells. However, TRAIL use as a stand alone therapeutic is hampered by the fact that many primary...

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Detalles Bibliográficos
Autores principales: Norian, Lyse A., Kucaba, Tamara A., Earel, James K., Knutson, Tina, vanOosten, Rebecca L., Griffith, Thomas S.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696620/
https://www.ncbi.nlm.nih.gov/pubmed/19547714
http://dx.doi.org/10.1155/2009/408038