Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-κB-dependent activation of the urokinase plasminogen activator system

Perioperative exposure to lipopolysaccharide (LPS) is associated with accelerated metastatic colorectal tumour growth. LPS directly affects cells through Toll-like receptor 4 (TLR-4) and the transcription factor NF-κB. The urokinase plasminogen activator (u-PA) system is intimately implicated in tum...

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Detalles Bibliográficos
Autores principales: Killeen, S D, Wang, J H, Andrews, E J, Redmond, H P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696751/
https://www.ncbi.nlm.nih.gov/pubmed/19436306
http://dx.doi.org/10.1038/sj.bjc.6604942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696751/
https://www.ncbi.nlm.nih.gov/pubmed/19436306
http://dx.doi.org/10.1038/sj.bjc.6604942

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