Targeting HSP90 for cancer therapy

Heat-shock proteins (HSPs) are molecular chaperones that regulate protein folding to ensure correct conformation and translocation and to avoid protein aggregation. Heat-shock proteins are increased in many solid tumours and haematological malignancies. Many oncogenic proteins responsible for the tr...

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Detalles Bibliográficos
Autores principales: Mahalingam, D, Swords, R, Carew, J S, Nawrocki, S T, Bhalla, K, Giles, F J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696754/
https://www.ncbi.nlm.nih.gov/pubmed/19401686
http://dx.doi.org/10.1038/sj.bjc.6605066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696754/
https://www.ncbi.nlm.nih.gov/pubmed/19401686
http://dx.doi.org/10.1038/sj.bjc.6605066

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