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Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer

Breast-conserving surgery followed by radiotherapy is effective in reducing recurrence; however, telangiectasia and fibrosis can occur as late skin side effects. As radiotherapy acts through producing DNA damage, we investigated whether genetic variation in DNA repair and damage response confers inc...

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Detalles Bibliográficos
Autores principales: Chang-Claude, J, Ambrosone, C B, Lilla, C, Kropp, S, Helmbold, I, von Fournier, D, Haase, W, Sautter-Bihl, M-L, Wenz, F, Schmezer, P, Popanda, O
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696768/
https://www.ncbi.nlm.nih.gov/pubmed/19367277
http://dx.doi.org/10.1038/sj.bjc.6605036