Wild-type but not mutant huntingtin modulates the transcriptional activity of liver X receptors

BACKGROUND: Huntington’s disease is caused by expansion of a polyglutamine tract found in the amino-terminal of the ubiquitously expressed protein huntingtin. Well studied in its mutant form, huntingtin has a wide variety of normal functions, loss of which may also contribute to disease progression....

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Detalles Bibliográficos
Autores principales: Futter, M, Diekmann, H, Schoenmakers, E, Sadiq, O, Chatterjee, K, Rubinsztein, D C
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696822/
https://www.ncbi.nlm.nih.gov/pubmed/19451134
http://dx.doi.org/10.1136/jmg.2009.066399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696822/
https://www.ncbi.nlm.nih.gov/pubmed/19451134
http://dx.doi.org/10.1136/jmg.2009.066399

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