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Restricted maximum likelihood estimation of genetic principal components and smoothed covariance matrices
Principal component analysis is a widely used 'dimension reduction' technique, albeit generally at a phenotypic level. It is shown that we can estimate genetic principal components directly through a simple reparameterisation of the usual linear, mixed model. This is applicable to any anal...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697245/ https://www.ncbi.nlm.nih.gov/pubmed/15588566 http://dx.doi.org/10.1186/1297-9686-37-1-1 |