Restricted maximum likelihood estimation of genetic principal components and smoothed covariance matrices

Principal component analysis is a widely used 'dimension reduction' technique, albeit generally at a phenotypic level. It is shown that we can estimate genetic principal components directly through a simple reparameterisation of the usual linear, mixed model. This is applicable to any anal...

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Detalles Bibliográficos
Autores principales: Meyer, Karin, Kirkpatrick, Mark
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697245/
https://www.ncbi.nlm.nih.gov/pubmed/15588566
http://dx.doi.org/10.1186/1297-9686-37-1-1