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Identification of the gene transcription repressor domain of Gli3

Gli transcription factors are downstream targets of the Hedgehog signaling pathway. Two of the three Gli proteins harbor gene transcription repressor function in the N-terminal half. We have analyzed the sequences and identified a potential repressor domain in Gli2 and Gli3 and have tested this expe...

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Detalles Bibliográficos
Autores principales: Tsanev, Robert, Tiigimägi, Piret, Michelson, Piret, Metsis, Madis, Østerlund, Torben, Kogerman, Priit
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697317/
https://www.ncbi.nlm.nih.gov/pubmed/19084012
http://dx.doi.org/10.1016/j.febslet.2008.12.010