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The human complement fragment receptor, C5L2, is a recycling decoy receptor

C5L2 is a 7 transmembrane domain receptor for complement fragment C5a that, unlike the classical C5a receptor, C5aR, does not couple to G proteins. However, in mice where C5L2 has been deleted, the response to C5a is altered, suggesting that C5L2 may have a signaling function. In order to investigat...

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Detalles Bibliográficos
Autores principales: Scola, Anne-Marie, Johswich, Kay-Ole, Morgan, B. Paul, Klos, Andreas, Monk, Peter N.
Formato: Texto
Lenguaje:English
Publicado: Pergamon Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697321/
https://www.ncbi.nlm.nih.gov/pubmed/19100624
http://dx.doi.org/10.1016/j.molimm.2008.11.001