Cargando…
Characteristics of compounds that cross the blood-brain barrier
Substances cross the blood-brain barrier (BBB) by a variety of mechanisms. These include transmembrane diffusion, saturable transporters, adsorptive endocytosis, and the extracellular pathways. Here, we focus on the chief characteristics of two mechanisms especially important in drug delivery: trans...
Autor principal: | |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697631/ https://www.ncbi.nlm.nih.gov/pubmed/19534732 http://dx.doi.org/10.1186/1471-2377-9-S1-S3 |