Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan

Uncoupling proteins (UCPs) can dissipate mitochondrial protonmotive force by increasing the proton conductance of the inner membrane and through this effect could decrease ROS production, ameliorate oxidative stress and extend lifespan. We investigated whether ubiquitous, pan-neuronal or neurosecret...

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Detalles Bibliográficos
Autores principales: Humphrey, Dickon M., Toivonen, Janne M., Giannakou, Maria, Partridge, Linda, Brand, Martin D.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698063/
https://www.ncbi.nlm.nih.gov/pubmed/19385039
http://dx.doi.org/10.1016/j.exger.2009.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698063/
https://www.ncbi.nlm.nih.gov/pubmed/19385039
http://dx.doi.org/10.1016/j.exger.2009.02.001

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