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Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis

Lrig1 is a marker of human interfollicular epidermal stem cells and helps maintain stem cell quiescence. We show that, in mouse epidermis, Lrig1 defines the hair follicle junctional zone adjacent to the sebaceous glands and infundibulum. Lrig1 is a Myc target gene; loss of Lrig1 increases the prolif...

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Detalles Bibliográficos
Autores principales: Jensen, Kim B., Collins, Charlotte A., Nascimento, Elisabete, Tan, David W., Frye, Michaela, Itami, Satoshi, Watt, Fiona M.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698066/
https://www.ncbi.nlm.nih.gov/pubmed/19427292
http://dx.doi.org/10.1016/j.stem.2009.04.014