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NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis

While the recognition of microbial infection often occurs at the cell surface via Toll-like receptors, the cytosol of the cell is also under surveillance for microbial products that breach the cell membrane. An important outcome of cytosolic recognition is the induction of IFNα and IFNβ, which are c...

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Detalles Bibliográficos
Autores principales: Pandey, Amit K., Yang, Yibin, Jiang, Zhaozhao, Fortune, Sarah M., Coulombe, Francois, Behr, Marcel A., Fitzgerald, Katherine A., Sassetti, Christopher M., Kelliher, Michelle A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698121/
https://www.ncbi.nlm.nih.gov/pubmed/19578435
http://dx.doi.org/10.1371/journal.ppat.1000500