The Wnt/β-Catenin Pathway Interacts Differentially with PTHrP Signaling to Control Chondrocyte Hypertrophy and Final Maturation

Sequential proliferation, hypertrophy and maturation of chondrocytes are required for proper endochondral bone development and tightly regulated by cell signaling. The canonical Wnt signaling pathway acts through β-catenin to promote chondrocyte hypertrophy whereas PTHrP signaling inhibits it by hol...

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Detalles Bibliográficos
Autores principales: Guo, Xizhi, Mak, Kinglun Kingston, Taketo, Makoto M., Yang, Yingzi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698152/
https://www.ncbi.nlm.nih.gov/pubmed/19557172
http://dx.doi.org/10.1371/journal.pone.0006067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698152/
https://www.ncbi.nlm.nih.gov/pubmed/19557172
http://dx.doi.org/10.1371/journal.pone.0006067

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