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Interaction with LC8 Is Required for Pak1 Nuclear Import and Is Indispensable for Zebrafish Development
Pak1 (p21 activated kinase 1) is a serine/threonine kinase implicated in regulation of cell motility and survival and in malignant transformation of mammary epithelial cells. In addition, the dynein light chain, LC8, has been described to cooperate with Pak1 in malignant transformation of breast can...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698211/ https://www.ncbi.nlm.nih.gov/pubmed/19557173 http://dx.doi.org/10.1371/journal.pone.0006025 |