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Interaction with LC8 Is Required for Pak1 Nuclear Import and Is Indispensable for Zebrafish Development

Pak1 (p21 activated kinase 1) is a serine/threonine kinase implicated in regulation of cell motility and survival and in malignant transformation of mammary epithelial cells. In addition, the dynein light chain, LC8, has been described to cooperate with Pak1 in malignant transformation of breast can...

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Detalles Bibliográficos
Autores principales: Lightcap, Christine M., Kari, Gabor, Arias-Romero, Luis E., Chernoff, Jonathan, Rodeck, Ulrich, Williams, John C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698211/
https://www.ncbi.nlm.nih.gov/pubmed/19557173
http://dx.doi.org/10.1371/journal.pone.0006025