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A Trivalent Virus-Like Particle Vaccine Elicits Protective Immune Responses against Seasonal Influenza Strains in Mice and Ferrets

There is need for improved human influenza vaccines, particularly for older adults who are at greatest risk for severe disease, as well as to address the continuous antigenic drift within circulating human subtypes of influenza virus. We have engineered an influenza virus-like particle (VLP) as a ne...

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Detalles Bibliográficos
Autores principales: Ross, Ted M., Mahmood, Kutub, Crevar, Corey J., Schneider-Ohrum, Kirsten, Heaton, Penny M., Bright, Rick A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698286/
https://www.ncbi.nlm.nih.gov/pubmed/19554101
http://dx.doi.org/10.1371/journal.pone.0006032