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A Trivalent Virus-Like Particle Vaccine Elicits Protective Immune Responses against Seasonal Influenza Strains in Mice and Ferrets
There is need for improved human influenza vaccines, particularly for older adults who are at greatest risk for severe disease, as well as to address the continuous antigenic drift within circulating human subtypes of influenza virus. We have engineered an influenza virus-like particle (VLP) as a ne...
Autores principales: | Ross, Ted M., Mahmood, Kutub, Crevar, Corey J., Schneider-Ohrum, Kirsten, Heaton, Penny M., Bright, Rick A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698286/ https://www.ncbi.nlm.nih.gov/pubmed/19554101 http://dx.doi.org/10.1371/journal.pone.0006032 |
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