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The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis
BACKGROUND: We previously showed that mice lacking the high mobility group A1 gene (Hmga1-knockout mice) developed a type 2-like diabetic phenotype, in which cell-surface insulin receptors were dramatically reduced (below 10% of those in the controls) in the major targets of insulin action, and gluc...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698822/ https://www.ncbi.nlm.nih.gov/pubmed/19460132 http://dx.doi.org/10.1186/1741-7007-7-24 |