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CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma

BACKGROUND: Renal cell carcinoma (RCC) is histopathologically heterogeneous with clear cell and papillary the most common subtypes. The most frequent molecular abnormality in clear cell RCC is VHL inactivation but promoter methylation of tumour suppressor genes is common in both subtypes of RCC. To...

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Detalles Bibliográficos
Autores principales: McRonald, Fiona E, Morris, Mark R, Gentle, Dean, Winchester, Laura, Baban, Dilair, Ragoussis, Jiannis, Clarke, Noel W, Brown, Michael D, Kishida, Takeshi, Yao, Masahiro, Latif, Farida, Maher, Eamonn R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698845/
https://www.ncbi.nlm.nih.gov/pubmed/19493342
http://dx.doi.org/10.1186/1476-4598-8-31