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Afferent signalling from the acid-challenged rat stomach is inhibited and gastric acid elimination is enhanced by lafutidine

BACKGROUND: Lafutidine is a histamine H(2 )receptor antagonist, the gastroprotective effect of which is related to its antisecretory activity and its ability to activate a sensory neuron-dependent mechanism of defence. The present study investigated whether intragastric administration of lafutidine...

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Detalles Bibliográficos
Autores principales: Edelsbrunner, Martin E, Nakano, Motoko, Holzer, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698872/
https://www.ncbi.nlm.nih.gov/pubmed/19490646
http://dx.doi.org/10.1186/1471-230X-9-40