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Can we apply the Mendelian randomization methodology without considering epigenetic effects?

INTRODUCTION: Instrumental variable (IV) methods have been used in econometrics for several decades now, but have only recently been introduced into the epidemiologic research frameworks. Similarly, Mendelian randomization studies, which use the IV methodology for analysis and inference in epidemiol...

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Detalles Bibliográficos
Autores principales: Ogbuanu, Ikechukwu U, Zhang, Hongmei, Karmaus, Wilfried
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698894/
https://www.ncbi.nlm.nih.gov/pubmed/19432981
http://dx.doi.org/10.1186/1742-7622-6-3