Silencing CD36 gene expression results in the inhibition of latent-TGF-β1 activation and suppression of silica-induced lung fibrosis in the rat

BACKGROUND: The biologically active form of transforming growth factor-β1 (TGF-β1) plays a key role in the development of lung fibrosis. CD36 is involved in the transformation of latent TGF-β1 (L-TGF-β1) to active TGF-β1. To clarify the role of CD36 in the development of silica-induced lung fibrosis...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Chen, Ying, Lv, Lina, Chen, Jie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698900/
https://www.ncbi.nlm.nih.gov/pubmed/19439069
http://dx.doi.org/10.1186/1465-9921-10-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698900/
https://www.ncbi.nlm.nih.gov/pubmed/19439069
http://dx.doi.org/10.1186/1465-9921-10-36

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