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Recent in vitro findings of negative inotropy of pantoprazole did not translate into clinically relevant effects on left ventricular function in healthy volunteers

PURPOSE: Reports on cardiac problems with oral proton pump inhibitors have caused extensive safety reviews by the US Food and Drug Administration. We provide additional data on acute cardiac effects of an intravenous application. METHODS: Echocardiography was performed in 18 healthy volunteers after...

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Detalles Bibliográficos
Autores principales: Schillinger, Wolfgang, Hörnes, Nina, Teucher, Nils, Sossalla, Samuel, Sehrt, Daniel, Jung, Klaus, Hünlich, Mark, Unsöld, Bernhard, Geiling, Bianca, Ramadori, Giuliano, Hilgers, Reinhard, Schwörer, Harald, Hasenfuss, Gerd
Formato: Texto
Lenguaje:English
Publicado: D. Steinkopff-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698968/
https://www.ncbi.nlm.nih.gov/pubmed/19301059
http://dx.doi.org/10.1007/s00392-009-0012-6