Metabolites of an Epac-Selective cAMP Analog Induce Cortisol Synthesis by Adrenocortical Cells through a cAMP-Independent Pathway

Adrenal zona fasciculata (AZF) cells express a cAMP-activated guanine nucleotide exchange protein (Epac2) that may function in ACTH-stimulated cortisol synthesis. Experiments were done to determine whether cAMP analogs that selectively activate Epacs could induce cortisol synthesis and the expressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Enyeart, Judith A., Enyeart, John J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698983/
https://www.ncbi.nlm.nih.gov/pubmed/19564912
http://dx.doi.org/10.1371/journal.pone.0006088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698983/
https://www.ncbi.nlm.nih.gov/pubmed/19564912
http://dx.doi.org/10.1371/journal.pone.0006088

Ejemplares similares