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The Dynamics of EBV Shedding Implicate a Central Role for Epithelial Cells in Amplifying Viral Output

To develop more detailed models of EBV persistence we have studied the dynamics of virus shedding in healthy carriers. We demonstrate that EBV shedding into saliva is continuous and rapid such that the virus level is replaced in ≤2 minutes, the average time that a normal individual swallows. Thus, t...

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Detalles Bibliográficos
Autores principales: Hadinoto, Vey, Shapiro, Michael, Sun, Chia Chi, Thorley-Lawson, David A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698984/
https://www.ncbi.nlm.nih.gov/pubmed/19578433
http://dx.doi.org/10.1371/journal.ppat.1000496