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Analysis of Pools of Targeted Salmonella Deletion Mutants Identifies Novel Genes Affecting Fitness during Competitive Infection in Mice

Pools of mutants of minimal complexity but maximal coverage of genes of interest facilitate screening for genes under selection in a particular environment. We constructed individual deletion mutants in 1,023 Salmonella enterica serovar Typhimurium genes, including almost all genes found in Salmonel...

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Detalles Bibliográficos
Autores principales: Santiviago, Carlos A., Reynolds, M. Megan, Porwollik, Steffen, Choi, Sang-Ho, Long, Fred, Andrews-Polymenis, Helene L., McClelland, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698986/
https://www.ncbi.nlm.nih.gov/pubmed/19578432
http://dx.doi.org/10.1371/journal.ppat.1000477