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Probing Natural Killer Cell Education by Ly49 Receptor Expression Analysis and Computational Modelling in Single MHC Class I Mice

Murine natural killer (NK) cells express inhibitory Ly49 receptors for MHC class I molecules, which allows for “missing self” recognition of cells that downregulate MHC class I expression. During murine NK cell development, host MHC class I molecules impose an “educating impact” on the NK cell pool....

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Detalles Bibliográficos
Autores principales: Johansson, Sofia, Salmon-Divon, Mali, Johansson, Maria H., Pickman, Yishai, Brodin, Petter, Kärre, Klas, Mehr, Ramit, Höglund, Petter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699029/
https://www.ncbi.nlm.nih.gov/pubmed/19557128
http://dx.doi.org/10.1371/journal.pone.0006046