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Linoleic Acid-Induced Mitochondrial Ca(2+) Efflux Causes Peroxynitrite Generation and Protein Nitrotyrosylation

It is well known that excessive non-esterified fatty acids in diabetes contribute to the pathogenesis of renal complications although the mechanism remains elusive. Enhanced oxidative stress has been hypothesized as a unified factor contributing to diabetic complications and increased protein nitrot...

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Detalles Bibliográficos
Autores principales: Zhang, Hong-Mei, Dang, Howard, Yeh, Chih-Ko, Zhang, Bin-Xian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699034/
https://www.ncbi.nlm.nih.gov/pubmed/19557129
http://dx.doi.org/10.1371/journal.pone.0006048