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Control of voltage-gated K(+) channel permeability to NMDG(+) by a residue at the outer pore
Crystal structures of potassium (K(+)) channels reveal that the selectivity filter, the narrow portion of the pore, is only ∼3-Å wide and buttressed from behind, so that its ability to expand is highly constrained, and the permeation of molecules larger than Rb(+) (2.96 Å in diameter) is prevented....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699102/ https://www.ncbi.nlm.nih.gov/pubmed/19332619 http://dx.doi.org/10.1085/jgp.200810139 |