SARS coronavirus spike protein-induced innate immune response occurs via activation of the NF-κB pathway in human monocyte macrophages in vitro

A purified recombinant spike (S) protein was studied for its effect on stimulating human peripheral blood monocyte macrophages (PBMC). We examined inflammatory gene mRNA abundances found in S protein-treated PBMC using gene arrays. We identified differential mRNA abundances of genes with functional...

Descripción completa

Detalles Bibliográficos
Autores principales: Dosch, Susan F., Mahajan, Supriya D., Collins, Arlene R.
Formato: Texto
Lenguaje:English
Publicado: Elsevier B.V. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699111/
https://www.ncbi.nlm.nih.gov/pubmed/19185596
http://dx.doi.org/10.1016/j.virusres.2009.01.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699111/
https://www.ncbi.nlm.nih.gov/pubmed/19185596
http://dx.doi.org/10.1016/j.virusres.2009.01.005

Ejemplares similares