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Syndecan-1 regulates α(v)β(3) and α(v)β(5) integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor
Syndecan-1 (Sdc1) is a matrix receptor shown to associate via its extracellular domain with the α(v)β(3) and α(v)β(5) integrins, potentially regulating cell adhesion, spreading, and invasion of cells expressing these integrins. Using Sdc1 deletion mutants expressed in human mammary carcinoma cells,...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699122/ https://www.ncbi.nlm.nih.gov/pubmed/19255147 http://dx.doi.org/10.1084/jem.20081278 |