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MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

The Mre11–Rad50–Nbs1 (MRN) complex functions in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) at postreplicative stages of the cell cycle. During HR, the MRN complex functions directly in the repair of DNA DSBs and in the initiation of DSB responses through activatio...

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Detalles Bibliográficos
Autores principales: Helmink, Beth A., Bredemeyer, Andrea L., Lee, Baeck-Seung, Huang, Ching-Yu, Sharma, Girdhar G., Walker, Laura M., Bednarski, Jeffrey J., Lee, Wan-Ling, Pandita, Tej K., Bassing, Craig H., Sleckman, Barry P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699138/
https://www.ncbi.nlm.nih.gov/pubmed/19221393
http://dx.doi.org/10.1084/jem.20081326