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A Systems Immunology Approach to the Host-Tumor Interaction: Large-Scale Patterns of Natural Autoantibodies Distinguish Healthy and Tumor-Bearing Mice

Traditionally, immunology has considered a meaningful antibody response to be marked by large amounts of high-affinity antibodies reactive with the specific inciting antigen; the detection of small amounts of low-affinity antibodies binding to seemingly unrelated antigens has been considered to be b...

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Detalles Bibliográficos
Autores principales: Merbl, Yifat, Itzchak, Royi, Vider-Shalit, Tal, Louzoun, Yoram, Quintana, Francisco J., Vadai, Ezra, Eisenbach, Lea, Cohen, Irun R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699142/
https://www.ncbi.nlm.nih.gov/pubmed/19557135
http://dx.doi.org/10.1371/journal.pone.0006053