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Reversion-induced LIM interaction with Src reveals a novel Src inactivation cycle

Aberrant Src activation plays prominent roles in cancer progression. However, how Src is activated in cancer cells is largely unknown. Genetic Src-activating mutations are rare and, therefore, are insufficient to account for Src activation commonly found in human cancers. In this study, we show that...

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Detalles Bibliográficos
Autores principales: Zhang, Yongjun, Tu, Yizeng, Zhao, Jianping, Chen, Ka, Wu, Chuanyue
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699145/
https://www.ncbi.nlm.nih.gov/pubmed/19307596
http://dx.doi.org/10.1083/jcb.200810155