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N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic
N-glycosylation, a common cotranslational modification, is thought to be critical for plasma membrane expression of glycoproteins by enhancing protein folding, trafficking, and stability through targeting them to the ER folding cycles via lectin-like chaperones. In this study, we show that N-glycans...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699153/ https://www.ncbi.nlm.nih.gov/pubmed/19307599 http://dx.doi.org/10.1083/jcb.200808124 |