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N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic

N-glycosylation, a common cotranslational modification, is thought to be critical for plasma membrane expression of glycoproteins by enhancing protein folding, trafficking, and stability through targeting them to the ER folding cycles via lectin-like chaperones. In this study, we show that N-glycans...

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Detalles Bibliográficos
Autores principales: Glozman, Rina, Okiyoneda, Tsukasa, Mulvihill, Cory M., Rini, James M., Barriere, Herve, Lukacs, Gergely L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699153/
https://www.ncbi.nlm.nih.gov/pubmed/19307599
http://dx.doi.org/10.1083/jcb.200808124