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Expression of Ebolavirus glycoprotein on the target cells enhances viral entry

BACKGROUND: Entry of Ebolavirus to the target cells is mediated by the viral glycoprotein GP. The native GP exists as a homotrimer on the virions and contains two subunits, a surface subunit (GP1) that is involved in receptor binding and a transmembrane subunit (GP2) that mediates the virus-host mem...

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Detalles Bibliográficos
Autores principales: Manicassamy, Balaji, Rong, Lijun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699336/
https://www.ncbi.nlm.nih.gov/pubmed/19505320
http://dx.doi.org/10.1186/1743-422X-6-75