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RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX

BACKGROUND: Modulation of chromatin structure has emerged as a critical molecular device to control gene expression. Histones undergo different post-translational modifications that increase chromatin accessibility to a number of regulatory factors. Among them, histone ubiquitination appears relevan...

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Detalles Bibliográficos
Autores principales: Pinato, Sabrina, Scandiuzzi, Cristina, Arnaudo, Nadia, Citterio, Elisabetta, Gaudino, Giovanni, Penengo, Lorenza
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699339/
https://www.ncbi.nlm.nih.gov/pubmed/19500350
http://dx.doi.org/10.1186/1471-2199-10-55