Modelling substrate specificity and enantioselectivity for lipases and esterases by substrate-imprinted docking

BACKGROUND: Previously, ways to adapt docking programs that were developed for modelling inhibitor-receptor interaction have been explored. Two main issues were discussed. First, when trying to model catalysis a reaction intermediate of the substrate is expected to provide more valid information tha...

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Detalles Bibliográficos
Autores principales: Juhl, P Benjamin, Trodler, Peter, Tyagi, Sadhna, Pleiss, Jürgen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699341/
https://www.ncbi.nlm.nih.gov/pubmed/19493341
http://dx.doi.org/10.1186/1472-6807-9-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699341/
https://www.ncbi.nlm.nih.gov/pubmed/19493341
http://dx.doi.org/10.1186/1472-6807-9-39

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